Radiometer logo

CRP (C-reactive protein)

The biomarker of choice to aid the diagnosis of infection and inflammatory disorders

  • Request more info about biomarkers

    I would like to know more about Radiometer biomarkers

    Contact details
    Workplace details

    By submitting this form, I acknowledge that I have reviewed and understood the data privacy notice.

    All fields must be filled!

  • See more products
  • Fast results
  • Early detection of inflammation
  • Evaluation of infection

CRP testing in the emergency department

When a patient is admitted with signs and symptoms of an infection, a C-reactive protein (CRP) test is used as an aid in the detection and evaluation of infection, tissue injury, inflammatory disorders, and associated diseases. CRP is valuable as an inflammation marker at the point-of-care, primary care and lab settings.

Increased CRP levels could be associated with bacterial, viral and fungal infections, sepsis, various forms of arthritis and several other infectious and inflammatory conditions [1]. CRP is an acute-phase protein produced by the liver and released into the blood a few hours after the onset of an infection, inflammation or tissue injury.

Because of the non-specific nature of the acute-phase response which leads to increased CRP levels, CRP should be used as a diagnostic aid in the clinical assessment of a patient [2].

Immunoassay products and solutions

CRP values for evaluation of infection

When faced with a patient with signs and symptoms of an infection, the physician faces the clinical dilemma of:

  • Administering antibiotics in a timely manner [3].
  • Avoiding inappropriate usage of antibiotics. Misuse of antibiotics when not required has contributed to the problem of multiresistant bacterial infections, which are very difficult to treat [4].

Interpreting the CRP value

  • Clinical cut-offs can be used to determine if the infection is bacterial or viral [5].

CRP test on the AQT90 FLEX analyzer

The AQT90 FLEX immunoassay analyzer is a benchtop analyzer that brings rapid biomarker assessment capabilities right to the patient’s bedside.

The AQT90 FLEX analyzer delivers quantitative results on the CRP assay in less than 13 minutes, accelerating infection and inflammatory disorder diagnosis in the ED to support rapid clinical decision making.

The AQT90 FLEX CRP assay can be used both in the lab and at the point of care without any sample or assay preparations, providing a fast result without any exposure to blood. Its closed tube system makes CRP testing easy: the operator simply inserts the sample tube into the tube holder in the sample port and the analyzer performs all assay steps automatically.  

All necessary reagents are included in the test cartridges, which remain stable onboard the analyzer for 20 days ensuring maximum availability and uptime.

Learn more about the AQT90 FLEX analyzer

Product image of the AQT90 FLEX analyzer from Radiometer

Key benefits of CRP on the AQT90 FLEX analyzer

  • No blood exposure: Closed system
  • No sample or assay preparation
  • Sample types: EDTA and lithium-heparin
  • Specimen types: Venous whole blood and plasma
  • Sample tubes: Fits most 13 × 75 mm standard tubes
  • No presence of hook effect, carry-over or known interferences

CRP assay specifics

Turnaround time:
< 13 min.
CV % (plasma): Within-lab CV% at conc. 7.4 mg/L: 5.3%
95th percentile*: < 5 mg/L
Traceability: Standardization: Calibration is traceable to ERM - DA472/IFCC.

* This value should only be used as an example. Each laboratory should establish its own decision threshold level.

References

1. Testing. com. C-Reactive Protein (CRP) Test. https://www.testing.com/tests/c-reactive-protein-crp/. Accessed July 2022.
2. Seeger C et al. Acute care testing handbook 2014.
3. Joo YM et al. Impact of timely antibiotic administration on outcomes in patients with severe sepsis and septic shock in the emergency department. Clinical and Experimental Emergency Medicine 2014;1, 1.
4. Lee Ventola C. The Antibiotic Resistance Crisis Part 1: Causes and Threats. P&T 2015; 40, 4.
5. Review Criteria for Assessment of C Reactive Protein (CRP), High Sensitivity C-Reactive Protein (hsCRP) and Cardiac C-Reactive Protein (cCRP) Assays - Guidance for Industry and FDA Staff. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/review-criteria-assessment-c-reactive-protein-crp-high-sensitivity-c-reactive-protein-hscrp-and. Assessed Dec 2020.

MAPSSS-000760 R1

Cookies are used on this website

Use of cookies
Don't show this message again
Confirm your account with Radiometer

Please enter a valid email

CONTINUE
By submitting your e-mail you agree to the data policy notice
Radiometer is using Microsoft Azure Active Directory to authenticate customer access. If you are already registered you will be taken to Microsoft AD to sign in using your Microsoft AD credentials.
You are already registered
SIGN IN
Radiometer is using Microsoft Azure AD to authenticate customer access. If you are already registered you will be taken to AZURE to sign in using your AZURE credentials.
Thank you

We will be sending an e-mail invitation to you shortly to sign in using Microsoft Azure AD.

CLOSE BANNER
Radiometer is using Microsoft Azure AD to authenticate customer access.
Sorry

It seems that your e-mail is not registered with us

TRY AGAIN CONTINUE
Radiometer is using Microsoft Azure AD to authenticate customer access. If your e-mail is not registered with us please click CONTINUE and we will guide you through the sign-in process.
We have previously sent an invitation by e-mail

Please click "Get started" in the e-mail to complete the registration process

RESEND E-MAIL
Radiometer is using Microsoft Azure AD to authenticate customer access.
Sorry

We were not able to process your request due to a communication error

TRY AGAIN
Sorry

It seems this account has not been given access to the portal

Continue

Radiometer is using Microsoft AZURE Active Directory to authenticate users

Radiometer uses Azure AD to provide our customers and partners secure access to documents, resources, and other services on our customer portal.

If your organization is already using Azure AD you can use the same credentials to access Radiometer's customer portal.

Key benefits

       
  • Allow the use of existing Active Directory credentials
  • Single-sign on experience
  • Use same credentials to access future services

Request access

You will receive an invitation to access our services via e-mail when your request has been approved.

When you accept the invitation, and your organization is already using AZURE AD, you can use the same credentials to access Radiometer's customer portal. Otherwise, a one-time password will be sent via e-mail to sign in.